Senator Mushahidullah Khan passed away in Islamabad early Thursday morning.
The news was initially confirmed by PML-N leader Mohammad Zubair.
Senator Mushahidullah was unwell for quite a long time, Zubair said, who is also the spokesperson for PML-N Vice-President Maryam Nawaz.
Mushahidullah used to come to the Senate sessions with great determination and courage, Zubair said, adding that the senator was a fearless man and stood firm against dictatorships.
The former Sindh governor added that the late senator, who was a federal minister under the previous government, was among the senior-most leaders of the party. His death, he said, is a great loss for his family, the PML-N and Pakistan.